Article

Tractometry-Based Quantification of Along-Tract White-Matter Hemispheric Asymmetry in Alzheimer’s Disease

2026-01-25

Abstract excerpt

White-matter hemispheric asymmetry is a fundamental property of human brain organization and is known to change in aging, neurodevelopment, and neurodegenerative disorders. Tractometry analyzes diffusion-derived microstructural measures along the full length of tracts, localizing changes to specific tract-segments rather than collapsing tracts into a single value. Yet, existing frameworks lack a principled way to...

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Literature Corpus work: 4bb82379-7d9a-5075-b28f-5338ab5e199a
DOI: 10.64898/2026.01.23.701434

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