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Natural mutations of human XDH promote the nitrite (NO 2 - )-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?

2023-03-24

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Several rare genetic variations of human XDH have been shown to alter xanthine oxidoreductase (XOR) activity leading to impaired purine catabolism. However, XOR is a multi-functional enzyme that depending upon the environmental conditions also expresses oxidase activity leading to both O ·- and H O and nitrite (·NO - ) reductase activity leading to NO. Since these products express important, and often diametric...

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Literature Corpus work: cc941585-85d9-5dd7-917e-4b73b9afe3b1
DOI: 10.1101/2023.03.24.533749

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Natural mutations of human XDH promote the nitrite (NO 2 - )-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?DOI 10.1101/2023.03.24.533749Read

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Natural mutations of human <i>XDH</i> promote the nitrite (NO <sub>2</sub> <sup>-</sup> )-reductase capacity of xanthine oxidoreductase: a novel mechanism to promote redox health?

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