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Article

Nox4 genetic inhibition in experimental hypertension and metabolic syndrome.

Archives of cardiovascular diseases - 1 Jan 2018

Bouabout Ghina, Ayme-Dietrich Estelle, Jacob Hugues, Champy Marie-France, Birling Marie-Christine, Pavlovic Guillaume, Madeira Lola, Fertak Lahcen El, Petit-Demoulière Benoit, Sorg Tania, Herault Yann, Mudgett John, Monassier Laurent

Abstract excerpt

BACKGROUND: Metabolic syndrome is a combination of symptoms including obesity, dyslipidaemia, glucose intolerance and hypertension. Oxidative stress appears to be a pathophysiological factor that links these signs and encourages progression towards heart failure and diabetes. Nox4 is a hydrogen peroxide nicotinamide adenine dinucleotide phosphate (NADPH) oxidase isoform - found in various cardiovascular cells and...

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Identifiers

PMID: 29113787
DOI: 10.1016/j.acvd.2017.03.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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