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Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness In Clinical Outcomes Following Stem Cell Transplantation

2016-11-21

Abstract excerpt

The quantitative relationship between the magnitude of variation in minor histocompatibility antigens (mHA) and graft versus host disease (GVHD) pathophysiology in stem cell transplant (SCT) donor-recipient pairs (DRP) is not established. In order to elucidate this relationship, whole exome sequencing (WES) was performed on 27 HLA matched related (MRD), & 50 unrelated donors (URD), to identify nonsynonymous single...

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Literature Corpus work
4e39d7f7-2d76-5eec-8b48-e80e0922bd0b
DOI
10.1101/088831
Open publication

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Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness In Clinical Outcomes Following Stem Cell TransplantationDOI 10.1101/088831
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