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Article

Whole exome sequencing to estimate alloreactivity potential between donors and recipients in stem cell transplantation.

British journal of haematology - 1 Aug 2014

Sampson Juliana K, Sheth Nihar U, Koparde Vishal N, Scalora Allison F, Serrano Myrna G, Lee Vladimir, Roberts Catherine H, Jameson-Lee Max, Ferreira-Gonzalez Andrea, Manjili Masoud H, Buck Gregory A, Neale Michael C, Toor Amir A

Abstract excerpt

Whole exome sequencing (WES) was performed on stem cell transplant donor-recipient (D-R) pairs to determine the extent of potential antigenic variation at a molecular level. In a small cohort of D-R pairs, a high frequency of sequence variation was observed between the donor and recipient exomes independent of human leucocyte antigen (HLA) matching. Nonsynonymous, nonconservative single nucleotide polymorphisms...

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Source

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Identifiers

PMID: 24749631
DOI: 10.1111/bjh.12898
PMCID: PMC4964978

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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