Article

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α3.7I form of α-thalassaemia using genome-wide microarray data

2021-09-22

Abstract excerpt

<h4>Background: </h4> The -α 3.7I -thalassaemia deletion is very common throughout Africa because it protects against malaria. When undertaking studies to investigate human genetic adaptations to malaria or other diseases, it is important to account for any confounding effects of α-thalassaemia to rule out spurious associations. <h4>Methods: </h4>: In this study, we have used direct α-thalassaemia genotyping to...

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Literature Corpus work: 4e1bb8dd-00a3-5da0-82db-50e004c2ee42
DOI: 10.12688/wellcomeopenres.16320.2

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Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α3.7I form of α-thalassaemia using genome-wide microarray dataDOI 10.12688/wellcomeopenres.16320.2Read

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