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Analytic optimization of<i>Plasmodium falciparum</i>marker gene haplotype recovery from amplicon deep sequencing of complex mixtures

2023-08-23

Abstract excerpt

Molecular epidemiologic studies of malaria parasites commonly employ amplicon deep sequencing (AmpSeq) of marker genes derived from dried blood spots (DBS) to answer public health questions related to topics such as transmission and drug resistance. As these methods are increasingly employed to inform direct public health action, it is important to rigorously evaluate the risk of false positive and false negative...

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Literature Corpus work
ee1c9742-212a-5eab-a758-2002053c0d96
DOI
10.1101/2023.08.17.23294237
Open publication

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