Article

<i>Entamoeba histolytica</i> adaption to auranofin: a phenotypic and multi-omics characterization

2021-06-23

Abstract excerpt

Auranofin (AF), an antirheumatic agent, targets mammalian thioredoxin reductase (TrxR), an important enzyme controlling redox homeostasisis, AF is also very effective against a diversity of pathogenic bacteria and protozoan parasites. Here, we report about the resistance of the parasite Entamoeba histolytica to 2 μM of AF that has been acquired by gradual exposure of the parasite to increasing amount of the drug....

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Literature Corpus work: 4e00561e-a795-5e20-8138-3e59d6999661
DOI: 10.1101/2021.06.23.449586

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