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Article

Endoplasmic reticulum stress-sensing mechanism is activated in Entamoeba histolytica upon treatment with nitric oxide.

PloS one - 1 Jan 2012

Santi-Rocca Julien, Smith Sherri, Weber Christian, Pineda Erika, Hon Chung-Chau, Saavedra Emma, Olivos-García Alfonso, Rousseau Sandrine, Dillies Marie-Agnès, Coppée Jean-Yves, Guillén Nancy

Abstract excerpt

The Endoplasmic Reticulum stores calcium and is a site of protein synthesis and modification. Changes in ER homeostasis lead to stress responses with an activation of the unfolded protein response (UPR). The Entamoeba histolytica endomembrane system is simple compared to those of higher eukaryotes, as a canonical ER is not observed. During amoebiasis, an infection of the human intestine and liver by E....

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PMID: 22384074
DOI: 10.1371/journal.pone.0031777
PMCID: PMC3286455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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