Article

Stress-responsive <i>Entamoeba</i> topoisomerase II: a potential anti-amoebic target

2019-06-21

Abstract excerpt

Topoisomerases are ubiquitous enzymes, involved in all DNA processes across the biological world. These enzymes are also targets for various anticancer and antimicrobial agents. The causative organism of amoebiasis, Entamoeba histolytica ( Eh ), has seven unexplored genes annotated as putative topoisomerases. One of the seven topoisomerases in this parasite was found to be highly up-regulated during heat shock a...

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Literature Corpus work: e342b0de-48a6-55ac-ba08-747e3bbf1cc9
DOI: 10.1101/679118

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