Article

Transcriptional profiling of the <i>Candida auris</i> response to exogenous farnesol exposure

2021-08-26

Abstract excerpt

The antifungal resistance threat posed by Candida auris necessitates bold and innovative therapeutic options. Farnesol, a quorum-sensing molecule with a potential antifungal and/or adjuvant effect; it may be a promising candidate in alternative treatment regimens. To gain further insights into the farnesol-related effect on C. auris , genome-wide gene expression analysis was performed using RNA-Seq. Farnesol exp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b9a06d82-d314-59ca-a126-078dfa0b9c28
DOI: 10.1101/2021.08.23.457447

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptional profiling of the <i>Candida auris</i> response to exogenous farnesol exposureDOI 10.1101/2021.08.23.457447Read

Abrogation of pathogenic attributes in drug resistant <i>Candida auris</i> strains by farnesolSemantic proximity Read

A Comparative Transcriptome Between Anti-drug Sensitive and Resistant Candida auris in ChinaSemantic proximity Read

Transcriptional response of <i>Candida auris</i> to the Mrr1 inducers methylglyoxal and benomylSemantic proximity Read

High-Throughput Profiling of Candida auris Isolates Reveals Clade-Specific Metabolic DifferencesSemantic proximity Read

Physiological and transcriptional profiling of surfactin exerted antifungal effect against <i>Candida albicans</i>Semantic proximity Read

Dry surface biofilm formation by <i>Candida auris</i> facilitates persistence and tolerance to sodium hypochloriteSemantic proximity Read

Role of zinc in growth, stress response and virulence gene expression of pathogenic Mucorale <i>Rhizopus arrhizus</i>Semantic proximity Read

Transcriptome Assembly and Profiling of Candida auris Reveals Novel Insights into Biofilm-Mediated ResistanceSemantic proximity Read

The Transcriptional Stress Response of Candida albicans to Weak Organic AcidsSemantic proximity Read

Copper Acts Synergistically with Fluconazole in <i>Candida glabrata</i> by Compromising Drug Efflux, Sterol Metabolism, and Zinc HomeostasisSemantic proximity Read

The oxidative stress response-related peroxiredoxin Tsa1b of <i>Candida auris</i> functions as a virulence factor that promotes infectionSemantic proximity Read

What makes <i>Candida auris</i> pan-drug resistant? Integrative insights from genomic, transcriptomic, and phenomic analysis of clinical strains resistant to all four major classes of antifungal drugsSemantic proximity Read