Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example.

The Biochemical journal - 15 Apr 2013

Schlosser Sarah, Leitsch David, Duchêne Michael

Abstract excerpt

Entamoeba histolytica, the causative agent of amoebiasis, possesses the dithiol-containing redox proteins Trx (thioredoxin) and TrxR (Trx reductase). Both proteins were found to be covalently modified and inactivated by metronidazole, a 5-nitroimidazole drug that is commonly used to treat infections with microaerophilic protozoan parasites in humans. Currently, very little is known about enzymes and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiprotozoal Agents
Share to Chromatography, Affinity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electrophoresis, Gel, Two-Dimensional

Share to Entamoeba histolytica

Share to Metronidazole

Share to Peroxiredoxins

Share to Thioredoxin-Disulfide Reductase

Share to Thioredoxins

Source

Identifiers

PMID: 23398389
DOI: 10.1042/BJ20121798

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Entamoeba histolytica: identification of thioredoxin-targeted proteins and analysis of serine acetyltransferase-1 as a prototype example.PMID 23398389Read ↗

<i>In-silico</i> prediction and modeling of the <i>Entamoeba histolytica</i> proteins: Serine-rich <i>Entamoeba histolytica</i> protein and peroxiredoxinSemantic proximity Read ↗

Identification of Entamoeba histolytica thiol-specific antioxidant as a GalNAc lectin-associated protein.Semantic proximity Read ↗

<i>Entamoeba histolytica</i>modulates a complex repertoire of novel genes in response to oxidative and nitrosative stresses: implications for amebic pathogenesisSemantic proximity Read ↗

Peroxiredoxins in ParasitesSemantic proximity Read ↗

Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia LinesSemantic proximity Read ↗

Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulenceSemantic proximity Read ↗

<i>Entamoeba histolytica</i> adaption to auranofin: a phenotypic and multi-omics characterizationSemantic proximity Read ↗

Identification of thioredoxin targeted proteins using thioredoxin single cysteine mutant-immobilized resin.Semantic proximity Read ↗

Differential Pathogenic Gene Expression of E. histolytica in Patients with Different Clinical Forms of AmoebiasisSemantic proximity Read ↗

Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolyticaSemantic proximity Read ↗

The role of thioredoxin proteins in <i>Mycobacterium tuberculosis</i> probed by proteome-wide target profilingSemantic proximity Read ↗

Mitochondrial sirtuin TcSir2rp3 affects TcSODA activity and oxidative stress response in <i>Trypanosoma cruzi</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.