Article

Development of in Vitro Resistance to Daptomycin in Enterococcus Faecium and Estimation of Its Fitness Cost

2020-12-02

Abstract excerpt

<title>Abstract</title> <p>BackgroundDaptomycin has broad-spectrum antibacterial activity against Gram-positive pathogens, but recent studies have revealed cases where daptomycin has failed to treat multidrug-resistant bacteria, such as vancomycin-resistant <italic>Enterococcus faecium</italic>. However, the resistance evolution of <italic>E</italic>. <italic>faecium</italic> to daptomycin<italic> in vitro</itali...

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Literature Corpus work: 4dab4283-fca2-5103-984a-e50c06d79563
DOI: 10.21203/rs.3.rs-116663/v1

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