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In-Host Evolution of Daptomycin Resistance and Heteroresistance in Methicillin-Resistant Staphylococcus aureus Strains From Three Endocarditis Patients

1 Nov 2019

Abstract excerpt

BACKGROUND: Daptomycin is considered an important alternative for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). However, treatment failures associated with daptomycin nonsusceptibility isolates have been reported in recent years. METHODS: In this study, we investigated serial MRSA strains from 3 endocarditis patients who had breakthrough bacteremia, despite treatment with daptomycin. The...

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Share to Antimicrobial Resistance in Staphylococcus
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PMID: 32176794
DOI: 10.1093/infdis/jiz571

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