Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness Cost

5 Dec 2017

Abstract excerpt

Daptomycin remains as one of the main treatment options for Methicillin Resistant Staphylococcus aureus (MRSA). Sporadic resistance cases reported in patients treated with either daptomycin or glycopeptides are a growing concern. In a previous study, we described a clinical case of a patient with a community-acquired MRSA infection resistant to daptomycin and with intermediate resistance to vancomycin who...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Bacterial biofilms and quorum sensing
Share to Bacterial Identification and Susceptibility Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29259579
DOI: 10.3389/fmicb.2017.02303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Daptomycin Resistance in Clinical MRSA Strains Is Associated with a High Biological Fitness CostPMID 29259579Read ↗

In-Host Evolution of Daptomycin Resistance and Heteroresistance in Methicillin-Resistant Staphylococcus aureus Strains From Three Endocarditis PatientsSemantic proximity Read ↗

Multiple pathways of cross-resistance to glycopeptides and daptomycin in persistent MRSA bacteraemia.Semantic proximity Read ↗

Development of in Vitro Resistance to Daptomycin in Enterococcus Faecium and Estimation of Its Fitness CostSemantic proximity Read ↗

Novel Daptomycin Tolerance and Resistance Mutations in Methicillin-Resistant Staphylococcus aureus from Adaptive Laboratory Evolution.Semantic proximity Read ↗

Acquisition of Daptomycin Resistance by Enterococcus faecium Confers Collateral Sensitivity to GlycopeptidesSemantic proximity Read ↗

Down-regulation of the two-component system and cell-wall biosynthesis-related genes was associated with the reversion to daptomycin susceptibility in daptomycin non-susceptible methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

Single nucleotide polymorphism leads to daptomycin resistance causing amino acid substitution-T345I in MprF of clinically isolated MRSA strains.Semantic proximity Read ↗

Phenotypic and genetic characterization of daptomycin non-susceptible Staphylococcus aureus strains selected by adaptive laboratory evolution.Semantic proximity Read ↗

Association of mprF mutations with cross-resistance to daptomycin and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA).Semantic proximity Read ↗

Varying fitness cost associated with resistance to fluoroquinolones governs clonal dynamic of methicillin-resistant Staphylococcus aureus.Semantic proximity Read ↗

In vivo development of daptomycin resistance in vancomycin-susceptible methicillin-resistant Staphylococcus aureus severe infections previously treated with glycopeptides.Semantic proximity Read ↗

Genetic Basis for Daptomycin Resistance in EnterococciSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.