Article

Genetic Architecture of Complex Traits and Disease Risk Predictors

2020-02-13

Abstract excerpt

Genomic prediction of complex human traits (e.g., height, cognitive ability, bone density) and disease risks (e.g., breast cancer, diabetes, heart disease, atrial fibrillation) has advanced considerably in recent years. Predictors have been constructed using penalized algorithms that favor sparsity: i.e., which use as few genetic variants as possible. We analyze the specific genetic variants (SNPs) utilized in the...

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Literature Corpus work: 4da11df1-314b-5a2c-9dff-ba36a260b78b
DOI: 10.1101/2020.02.12.946608

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