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Article

Performance and robustness of penalized and unpenalized methods for genetic prediction of complex human disease.

Genetic epidemiology - 1 Feb 2013

Abraham Gad, Kowalczyk Adam, Zobel Justin, Inouye Michael

Abstract excerpt

A central goal of medical genetics is to accurately predict complex disease from genotypes. Here, we present a comprehensive analysis of simulated and real data using lasso and elastic-net penalized support-vector machine models, a mixed-effects linear model, a polygenic score, and unpenalized lo...

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Identifiers

PMID: 23203348
DOI: 10.1002/gepi.21698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23203348-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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