Article

Activity drives local CaMKII synthesis and subcellular localization via autophosphorylation-dependent pathways

2025-11-04

Abstract excerpt

Strong repeated stimulation of a neuron triggers an increase in local protein synthesis along with a change in localization of proteins, allowing the neuron to rapidly adjust its proteome in response to activity. One of these proteins, calcium/calmodulin-dependent protein kinase II (CaMKII), is involved in mediating structural and functional changes after activity. While postsynaptic CaMKII translation has been st...

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Literature Corpus work: 4d26b190-c95d-5cab-a17a-2c5a13a49b66
DOI: 10.1101/2025.11.03.686364

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