Article
Postsynaptic translation affects the efficacy and morphology of neuromuscular junctions.
Nature - 29 Jun 2000
Sigrist S J, Thiel P R, Reiff D F, Lachance P E, Lasko P, Schuster C M
Abstract excerpt
Long-term synaptic plasticity may be associated with structural rearrangements within the neuronal circuitry. Although the molecular mechanisms governing such activity-controlled morphological alterations are mostly elusive, polysomal accumulations at the base of developing dendritic spines and the activity-induced synthesis of synaptic components suggest that localized translation is involved during synaptic...
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