Article

Local translation provides the asymmetric distribution of CaMKII required for associative memory formation

2022-03-29

Abstract excerpt

<h4>SUMMARY</h4> How compartment-specific local proteomes are generated and maintained is inadequately understood, particularly in neurons, which display extreme asymmetries. Here we show that local enrichment of Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) in axons of Drosophila mushroom body neurons is necessary for cellular plasticity and associative memory formation. Enrichment is achieved via enh...

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Literature Corpus work: 6c327587-5922-538f-ba9b-7cfd5dfb0b25
DOI: 10.1101/2022.03.28.486096

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