Article

Impaired spatial coding and neuronal hyperactivity in the medial entorhinal cortex of aged <i> App <sup>NL-G-F</sup> </i> mice

2024-11-26

Abstract excerpt

The progressive accumulation of amyloid beta (Aβ) pathology in the brain has been associated with aberrant neuronal network activity and poor cognitive performance in preclinical mouse models of Alzheimer’s disease (AD). Presently, our understanding of the mechanisms driving pathology-associated neuronal dysfunction and impaired information processing in the brain remains incomplete. Here, we assessed the impact o...

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Literature Corpus work: 4cff31cb-1f57-5450-9d71-e53872040d02
DOI: 10.1101/2024.11.26.624990

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