Article

Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neurons

2023-09-05

Abstract excerpt

<h4>ABSTRACT</h4> The homeostatic regulation of neuronal activity is essential for robust computation; key set-points, such as firing rate, are actively stabilized to compensate for perturbations. From this perspective, the disruption of brain function central to neurodegenerative disease should reflect impairments of computationally essential set-points. Despite connecting neurodegeneration to functional outcome...

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Literature Corpus work: 9beccb91-c011-512b-8d5b-93184577fe9d
DOI: 10.1101/2023.09.01.555947

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