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HSPA12A promotes c-Myc lactylation-mediated proliferation of tubular epithelial cell to facilitate renal functional recovery from kidney ischemia/reperfusion injury

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>Proliferation of renal tubular epithelial cells (TEC) is essential to restore tubular integrity and thereby to support renal functional recovery from kidney ischemia/reperfusion (KI/R) injury. The transcriptional factor c-Myc is activated for TEC proliferation following KI/R; however, the in-depth mechanism of c-Myc activation in TEC following KI/R is incompletely known. Heat shock prot...

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Literature Corpus work
4cde5811-78d4-5282-a509-bed76f75772c
DOI
10.21203/rs.3.rs-4633628/v1
Open publication

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HSPA12A promotes c-Myc lactylation-mediated proliferation of tubular epithelial cell to facilitate renal functional recovery from kidney ischemia/reperfusion injuryDOI 10.21203/rs.3.rs-4633628/v1
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