Article

KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy

2022-11-29

Abstract excerpt

<title>Abstract</title> <p>Hepatic ischemia-reperfusion (I/R) injury, a common clinical complication of liver transplantation, gravely affects patient prognosis. Krüppel-like factors (KLFs) are a family of C2/H2 zinc finger DNA-binding proteins. KLF6, a member of the KLF family proteins, plays crucial roles in proliferation, metabolism, inflammation and injury responses; however, its role in HIR largely remains u...

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Literature Corpus work: 8114c24b-3a3b-5001-b579-49af36954f93
DOI: 10.21203/rs.3.rs-2212760/v1

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