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Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair

28 Feb 2019

Abstract excerpt

Acute kidney injury (AKI) is a major kidney disease characterized by an abrupt loss of renal function. Accumulating evidence indicates that incomplete or maladaptive repair after AKI can result in kidney fibrosis and the development and progression of chronic kidney disease (CKD). Hypoxia, a condition of insufficient supply of oxygen to cells and tissues, occurs in both acute and chronic kidney diseases under a...

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PMID: 30823476
DOI: 10.3390/cells8030207

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