Article
CHOP-mediated Gasdermin E expression promotes pyroptosis, inflammation, and mitochondrial damage in renal ischemia-reperfusion injury
2023-10-14
Abstract excerpt
<title>Abstract</title> <p>In clinical practice, renal ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI), often leading to acute renal failure or end-stage renal disease (ESRD). The current understanding of renal IRI mechanisms remains unclear, and effective therapeutic strategies and clear targets are lacking. Therefore, the need to find explicit and effective ways to reduce renal...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- df5e44e5-4181-5952-901f-7907fd61d32e
- DOI
- 10.21203/rs.3.rs-3380049/v1
