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Article

Induction of type I and III interferons by viral and endogenous stimuli in systemic sclerosis

2025-09-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> The interferon (IFN) system is activated in systemic sclerosis (SSc), but the driving mechanisms remain unclear. We asked whether type I and III IFN responses to Toll-like receptor (TLR)-7/8/9 stimulation of leukocytes from patients with SSc differ from healthy individuals, and if the IFN production is associated with clinical features. <h4>Methods</h4> Peripheral blood mono...

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Literature Corpus work
4cd7f8a9-f030-508e-9eb2-213817a09781
DOI
10.1101/2025.09.23.25336432
Open publication

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Induction of type I and III interferons by viral and endogenous stimuli in systemic sclerosisDOI 10.1101/2025.09.23.25336432
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