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Article

Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?

21 Aug 2019

Abstract excerpt

PURPOSE OF REVIEW: The role of type I IFNs (IFN-I) in the promotion of autoimmunity has been well established. However, its role in the skin fibrosis of systemic sclerosis (SSc) is less clear. IFN-I can participate to tissue repair, and, here, we will consider the extent to which IFN-I's role in SSc skin fibrosis may reflect in part IFN-I functions during wound healing. RECENT FINDINGS: Studies are beginning to...

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Identifiers

PMID: 31436583
DOI: 10.1097/bor.0000000000000659

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