Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of Type 1 Interferon in Systemic Sclerosis

1 Jan 2013

Abstract excerpt

Systemic Sclerosis (Scleroderma, SSc) is an autoimmune disease characterized by vasculopathy, inflammation, and fibrosis that can lead to loss of organ function. Type I interferons (IFNs) are family of cytokines that mitigate the deleterious effects of viral and bacterial infections in the innate immunity system. Past several years, research efforts have been focused on the role of type I IFN and IFN-inducible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eosinophilic Disorders and Syndromes
Share to Systemic Lupus Erythematosus Research
Share to Systemic Sclerosis and Related Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24046769
DOI: 10.3389/fimmu.2013.00266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of Type 1 Interferon in Systemic SclerosisPMID 24046769Read ↗

Type 1 interferon activation in systemic sclerosis: a biomarker, a target or the culpritSemantic proximity Read ↗

Induction of type I and III interferons by viral and endogenous stimuli in systemic sclerosisSemantic proximity Read ↗

Type I Interferons in the Pathogenesis and Treatment of Autoimmune Diseases.Semantic proximity Read ↗

Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory GenesSemantic proximity Read ↗

Polymorphisms in STAT4 and IRF5 increase the risk of systemic sclerosis: a meta-analysis.Semantic proximity Read ↗

Systemic sclerosis and lupus: points in an interferon-mediated continuum.Semantic proximity Read ↗

Multiple genes, especially immune-regulating genes, contribute to disease susceptibility in systemic sclerosis.Semantic proximity Read ↗

The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.Semantic proximity Read ↗

Systemic sclerosis pathogenesis: contribution of recent advances in genetics.Semantic proximity Read ↗

STAT4 is a genetic risk factor for systemic sclerosis having additive effects with IRF5 on disease susceptibility and related pulmonary fibrosis.Semantic proximity Read ↗

The Long Non-coding RNA NRIR Drives IFN-Response in Monocytes: Implication for Systemic SclerosisSemantic proximity Read ↗

Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.