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Article

Role of toll-like receptors in systemic sclerosis

1 Jan 2013

Abstract excerpt

Accumulative evidence demonstrates the crucial role of evolutionary conserved Toll-like receptors (TLRs) in identifying microbial or viral compounds. TLRs are also able to recognise endogenous molecules which are released upon cell damage or stress and have been shown to play a key role in numerous autoimmune diseases including systemic sclerosis (SSc). A classic feature of SSc, is vascular injury manifested as...

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PMID: 23985302
DOI: 10.1017/erm.2013.10

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