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Article

Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma.

The Journal of investigative dermatology - 1 Apr 2014

Farina Antonella, Cirone Mara, York Michael, Lenna Stefania, Padilla Cristina, Mclaughlin Sarah, Faggioni Alberto, Lafyatis Robert, Trojanowska Maria, Farina Giuseppina A

Abstract excerpt

Scleroderma (SSc) is a complex and heterogeneous connective tissue disease mainly characterized by autoimmunity, vascular damage, and fibrosis that mostly involve the skin and lungs. Epstein-Barr virus (EBV) is a lymphotropic γ-herpesvirus that has co-evolved with human species, infecting >95% of the adult population worldwide, and has been a leading candidate in triggering several autoimmune diseases. Here we...

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Identifiers

PMID: 24129067
DOI: 10.1038/jid.2013.423
PMCID: PMC3961515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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