Article

DNA Methylation in Cocaine Use Disorder – An Epigenome-wide Approach in the Human Prefrontal Cortex

2022-11-05

Abstract excerpt

Cocaine use disorder (CUD) is characterized by a loss of control over drug intake and is associated with structural, functional, and molecular alterations in the brain. At the molecular level, epigenetic alterations are hypothesized to contribute to the higher-level functional and structural brain changes as observed in CUD. Most evidence of cocaine-associated epigenetic changes comes from animal studies while onl...

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Literature Corpus work: 4cccc58f-b759-5b69-9b21-48b59dd924c5
DOI: 10.1101/2022.11.05.22281974

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