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Article

Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse.

Epigenetics - 1 Oct 2022

Alrfooh Aysheh, Smith Ryan M

Abstract excerpt

Despite more than 2 million American cocaine users monthly, there is no approved drug for treating cocaine use disorder. Cocaine use disorder has a multifactorial aetiology, including both genetic and environmental factors. Both cocaine use and genetic variations demonstrably alter DNA methylation and gene expression in the brain in a complex manner. How these factors interact in the context of cocaine abuse in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34813393
DOI: 10.1080/15592294.2021.2005277
PMCID: PMC9543049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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