Article

Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder

2024-04-24

Abstract excerpt

Structural and functional changes of the brain are assumed to contribute to excessive cocaine intake, craving, and relapse in cocaine use disorder (CUD). Epigenetic and transcriptional changes were hypothesized as a molecular basis for CUD-associated brain alterations. Here we performed a multi-omics study of CUD by integrating epigenome-wide methylomic (N=42) and transcriptomic (N=25) data from the same individua...

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Literature Corpus work: dcbdedbc-a469-5a2e-b504-3c2fc12e3b10
DOI: 10.1101/2024.04.24.24306302

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