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CD73 (Cluster of Differentiation 73) and the Differences Between Mice and Humans

24 Jan 2019

Abstract excerpt

As vascular disease is complex and the various manifestations are influenced by differences in vascular bed architecture, exposure to shear and mechanical forces, cell types involved, and inflammatory responses, in vivo models are necessary to recapitulate the complex physiology and dynamic cellular interactions during pathogenesis. Murine knockout models are commonly used tools for investigators to study the...

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PMID: 30676071
DOI: 10.1161/atvbaha.118.311579

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