Article

Adenine-induced kidney disease alters the cortical bone metabolome of C57BL/6J mice in a manner that depends on sex

2025-06-03

Abstract excerpt

Chronic kidney disease (CKD) increases the likelihood of bone fracture as well as post-fracture mortality. The loss of bone fracture resistance in CKD results from both a loss of bone mass and decreased bone material properties, which together result from changes to the health and activities of bone cells. Determining changes to bone tissue metabolism with CKD may reveal insights important to monitoring and mitiga...

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Literature Corpus work: 2212dd2f-ccfa-51c6-8ba7-a65091e48482
DOI: 10.1101/2025.06.02.657438

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