Article

CT-FOCS: a novel method for inferring cell type-specific enhancer-promoter maps

2019-07-18

Abstract excerpt

<h4>ABSTRACT</h4> Spatiotemporal gene expression patterns are governed to a large extent by the activity of enhancer elements, which engage in physical contacts with their target genes. Identification of enhancer-promoter (EP) links that are functional only in a specific subset of cell types is a key challenge in understanding gene regulation. We introduce CT-FOCS, a statistical inference method that uses linear...

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Literature Corpus work: 89497de5-36d3-5cff-9082-ec6a0ed8de7e
DOI: 10.1101/707158

Open publication

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