Article

Gastrodin attenuates diabetic cardiomyopathy characterised by myocardial fibrosis by inhibiting the KLK8-PAR1 signalling axis

2024-09-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Diabetic cardiomyopathy (DCM), which is characterised by myocardial fibrosis, is a major cause of mortality and morbidity in diabetic patients, and inhibition of cardiac fibrosis is a fundamental strategy for the treatment of DCM. Gastrodin (GAS), a compound extracted from Gastrodia elata, has a protective effect against DCM, but the molecular mechanism by which...

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Literature Corpus work: 641b546b-1856-5638-8694-810e31412110
DOI: 10.21203/rs.3.rs-4736363/v1

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