Article

Identification of tumor initiating cells and early marker genes in normal colonic epithelium that lead to neoplastic transformation

2025-10-27

Abstract excerpt

<title>Abstract</title> <p> <bold>Background & Aims</bold> : Colorectal cancer (CRC) remains a major cause of cancer-related morbidity and mortality worldwide. Although the adenoma-carcinoma sequence and associated genetic alterations are well characterized, the earliest cellular and molecular events that initiate tumorigenesis within histologically normal colonic epithelium remain poorly defined. This study ai...

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Literature Corpus work: 4c07d081-9ad8-5066-8bef-351d73f8b682
DOI: 10.21203/rs.3.rs-7914753/v1

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