Article

Tumor Microenvironment in Ovarian Cancer through Spatial Transcriptomics and Identification of Key Gene Expression Profiles

2025-04-28

Abstract excerpt

Ovarian cancer exhibits marked heterogeneity within its complex tumor microenvironment, driving progression, metastasis, and therapeutic resistance. This study presents a novel integration of spatial transcriptomics with single-cell RNA sequencing to comprehensively characterize the molecular landscape of ovarian cancer tissues. Employing the Leiden clustering algorithm at an optimal resolution of 0.7, we identifi...

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Literature Corpus work: 4c066672-7d2f-5249-b6b4-748abc36e042
DOI: 10.1101/2025.04.25.650590

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