Article

Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephalitis in seven new cohorts

2025-09-04

Abstract excerpt

Mosquito-borne West Nile virus (WNV) infection is a growing global health problem. About 0.5% of infected individuals develop encephalitis. We previously showed that 40% of patients in six cohorts had WNV encephalitis because of circulating auto-antibodies (auto-Abs) neutralizing type I IFNs. In seven new cohorts, we found that the prevalence of auto-Abs was highest (40% [17-44%]) in patients with encephalitis, an...

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Literature Corpus work: 4bffbc77-64bf-5817-bc2c-4c625f11093c
DOI: 10.1101/2025.08.31.25334556

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