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Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus encephalitis or myelitis

2026-07-27

Abstract excerpt

Chikungunya virus (CHIKV) infection is typically not life-threatening but may, in rare cases, affect the central nervous system (CNS). In three cohorts of confirmed CHIKV cases from Martinique (French overseas territory) and Brazil (patients aged 0–89 years, n = 245), 20 patients had CNS infection (aged 17–87 years). Autoantibodies neutralizing type I interferons (AAN-I-IFN) were found in 35% of patients (4 male...

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Literature Corpus work: 25bdcf82-d0b5-599b-9bde-82d80ae420da
DOI: 10.64898/2026.07.23.26358609

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