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Neurologic complications in herpes simplex encephalitis: clinical, immunological and genetic studies

15 Jul 2023

Abstract excerpt

Patients with herpes simplex virus (HSV) encephalitis (HSE) often develop neuronal autoantibody-associated encephalitis (AE) post-infection. Risk factors of AE are unknown. We tested the hypotheses that predisposition for AE post-HSE may be involved, including genetic variants at specific loci, human leucocyte (HLA) haplotypes, or the blood innate immune response against HSV, including type I interferon (IFN)...

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PMID: 37453099
DOI: 10.1093/brain/awad238

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