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Protective capacity and epitope specificity of CD8<sup>+</sup> T cells responding to lethal West Nile virus infection

11 Jun 2007

Abstract excerpt

West Nile virus (WNV) is a small, positive-strand RNA virus belonging to the Flaviviridae genus, which causes lethal encephalitis in a subset of infected birds and mammals. In humans, WNV exhibits pronounced age-related morbidity and mortality, but the basis of this effect is unclear, and the molecular and cellular parameters of the host-WNV infection are just beginning to be elucidated. Indeed, numerous...

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PMID: 17559175
DOI: 10.1002/eji.200737196

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