Article

The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

2022-01-14

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across age groups. In the general population, they are found in ~1% of individuals aged 20-70 years and in >4% of those >70 years old. With a sample of 1,261 deceased patients and 34...

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Literature Corpus work: b9bed375-1c6f-5d77-83ed-df9b6053b977
DOI: 10.21203/rs.3.rs-1225906/v1

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