Article

The temporal dynamics of the immune response to neoadjuvant androgen deprivation therapy suggests a window-of-opportunity for checkpoint inhibitor therapy in prostate cancer

2026-01-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Novel therapies to prevent lethal castration resistant prostate cancer in response to standard-of-care androgen deprivation therapy (ADT) are required. Unfortunately, most prostate cancers are “immune cold” and fail to respond to checkpoint inhibitors (CPIs). To assess whether ADT induces changes that enable more effective CPI therapy, we examined the tumor immune micro-environ...

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Literature Corpus work: 4bba247a-81f0-517b-a747-967a093e9658
DOI: 10.64898/2026.01.10.26343859

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