Article

Genome-wide association analysis of the human thalamus identifies novel genomic loci and reveals genetic overlap with distinct cortical regions and ten brain disorders

2020-09-18

Abstract excerpt

The thalamus is a vital communication hub in the center of the brain and consists of distinct nuclei critical for consciousness and higher-order cortical functions 1-8 . Structural and functional thalamic alterations are involved in the pathogenesis of common brain disorders 9-12 , yet the genetic architecture of the thalamus remains largely unknown. Here, using brain scans and genotype data from 30,114 individual...

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Literature Corpus work: 4baac024-48bd-5d6d-aeae-a2fe77b3e2fa
DOI: 10.1101/2020.09.16.20192898

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