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Article

The genetic architecture of the human thalamus and its overlap with ten common brain disorders.

Nature communications - 18 May 2021

Elvsåshagen Torbjørn, Shadrin Alexey, Frei Oleksandr, van der Meer Dennis, Bahrami Shahram, Kumar Vinod Jangir, Smeland Olav, Westlye Lars T, Andreassen Ole A, Kaufmann Tobias

Abstract excerpt

The thalamus is a vital communication hub in the center of the brain and consists of distinct nuclei critical for consciousness and higher-order cortical functions. Structural and functional thalamic alterations are involved in the pathogenesis of common brain disorders, yet the genetic architecture of the thalamus remains largely unknown. Here, using brain scans and genotype data from 30,114 individuals, we...

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Source

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Identifiers

PMID: 34006833
DOI: 10.1038/s41467-021-23175-z
PMCID: PMC8131358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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