Concordance of genetic variation that increases risk for Tourette Syndrome and that influences its underlying neurocircuitry

Abstract excerpt

Abstract There have been considerable recent advances in understanding the genetic architecture of Tourette Syndrome (TS) as well as its underlying neurocircuitry. However, the mechanisms by which genetic variation that increases risk for TS—and its main symptom dimensions—influence relevant brain regions are poorly understood. Here we undertook a genome-wide investigation of the overlap between TS genetic risk...

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