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Article

A schizophrenia-associated HLA locus affects thalamus volume and asymmetry.

Brain, behavior, and immunity - 1 May 2015

Brucato Nicolas, Guadalupe Tulio, Franke Barbara, Fisher Simon E, Francks Clyde

Abstract excerpt

Genes of the Major Histocompatibility Complex (MHC) have recently been shown to have neuronal functions in the thalamus and hippocampus. Common genetic variants in the Human Leukocyte Antigens (HLA) region, human homologue of the MHC locus, are associated with small effects on susceptibility to schizophrenia, while volumetric changes of the thalamus and hippocampus have also been linked to schizophrenia. We...

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Identifiers

PMID: 25728236
DOI: 10.1016/j.bbi.2015.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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